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. 2020 Jan 25;8(3):e1126. doi: 10.1002/mgg3.1126

Table 2.

Enriched Go terms of the DEGs

  Category Term Count % p‐Value FDR
Up regulated GOTERM_BP_DIRECT GO:0051301~cell division 6 0.142993327 4.04E‐06 0.004971483
GOTERM_BP_DIRECT GO:0006355~regulation of transcription DNA‐templated 7 0.166825548 3.53E‐04 0.432578524
GOTERM_BP_DIRECT GO:0006281~DNA repair 4 0.095328885 8.15E‐04 0.997007591
GOTERM_BP_DIRECT GO:0045143~homologous chromosome segregation 2 0.047664442 .006639221 7.86341138
GOTERM_BP_DIRECT GO:0031536~positive regulation of exit from mitosis 2 0.047664442 .008292426 9.731016783
GOTERM_BP_DIRECT GO:0007067~mitotic nuclear division 3 0.071496663 .013030094 14.89218414
GOTERM_BP_DIRECT GO:0046323~glucose import 2 0.047664442 .018156528 20.17047326
GOTERM_BP_DIRECT GO:0051276~chromosome organization 2 0.047664442 .023053317 24.9298377
GOTERM_BP_DIRECT GO:0070979~protein K11‐linked ubiquitination 2 0.047664442 .037603917 37.57710332
GOTERM_BP_DIRECT GO:0007052~mitotic spindle organization 2 0.047664442 .037603917 37.57710332
GOTERM_BP_DIRECT GO:0090307~mitotic spindle assembly 2 0.047664442 .045597774 43.66110836
GOTERM_CC_DIRECT GO:0005737~cytoplasm 15 0.357483317 2.21E‐05 0.022280174
GOTERM_CC_DIRECT GO:0005634~nucleus 14 0.333651096 5.40E‐05 0.054460588
GOTERM_CC_DIRECT GO:0043203~axon hillock 2 0.047664442 .00741693 7.237425098
GOTERM_CC_DIRECT GO:0032133~chromosome passenger complex 2 0.047664442 .00741693 7.237425098
GOTERM_CC_DIRECT GO:0005654~nucleoplasm 7 0.166825548 .010502317 10.10650713
GOTERM_CC_DIRECT GO:0045120~pronucleus 2 0.047664442 .013312558 12.64989615
GOTERM_CC_DIRECT GO:0051233~spindle midzone 2 0.047664442 .022093237 20.18460143
GOTERM_MF_DIRECT GO:0031625~ubiquitin protein ligase binding 3 0.076628352 .011662791 10.93819391
GOTERM_MF_DIRECT GO:0008301~DNA binding bending 2 0.051085568 .015851015 14.59560577
GOTERM_MF_DIRECT GO:0005524~ATP binding 6 0.153256705 .027091606 23.75384229
GOTERM_MF_DIRECT GO:0030414~peptidase inhibitor activity 2 0.051085568 .030054212 26.01571812
GOTERM_MF_DIRECT GO:0061631~ubiquitin conjugating enzyme activity 2 0.051085568 .038482685 32.12464677
Down regulated GOTERM_BP_DIRECT GO:0070836~caveola assembly 3 0.046260601 6.99E−05 0.098559412
GOTERM_BP_DIRECT GO:0007155~cell adhesion 6 0.092521203 .007419687 9.977332032
GOTERM_BP_DIRECT GO:0019065~receptor‐mediated endocytosis of virus by host cell 2 0.030840401 .008018493 10.74080337
GOTERM_BP_DIRECT GO:0042420~dopamine catabolic process 2 0.030840401 .013329193 17.25342044
GOTERM_BP_DIRECT GO:0042135~neurotransmitter catabolic process 2 0.030840401 .021243157 26.14357095
GOTERM_BP_DIRECT GO:0050891~multicellular organismal water homeostasis 2 0.030840401 .021243157 26.14357095
GOTERM_BP_DIRECT GO:0001525~angiogenesis 4 0.061680802 .021777665 26.71078904
GOTERM_BP_DIRECT GO:0032060~bleb assembly 2 0.030840401 .026484616 31.53390357
GOTERM_BP_DIRECT GO:0006069~ethanol oxidation 2 0.030840401 .031698626 36.53140253
GOTERM_BP_DIRECT GO:0015793~glycerol transport 2 0.030840401 .034295382 38.89185575
GOTERM_BP_DIRECT GO:0009992~cellular water homeostasis 2 0.030840401 .034295382 38.89185575
GOTERM_CC_DIRECT GO:0070062~extracellular exosome 16 0.246723207 .001317986 1.408901211
GOTERM_CC_DIRECT GO:0005886~plasma membrane 19 0.292983809 .003743762 3.955034143
GOTERM_CC_DIRECT GO:0005901~caveola 3 0.046260601 .010295194 10.53630766
GOTERM_CC_DIRECT GO:0005576~extracellular region 10 0.154202005 .01150877 11.70950819
GOTERM_CC_DIRECT GO:0045121~membrane raft 4 0.061680802 .012603718 12.75603307
GOTERM_CC_DIRECT GO:0045177~apical part of cell 3 0.046260601 .013532583 13.63498448
GOTERM_CC_DIRECT GO:0016021~integral component of membrane 20 0.308404009 .018955008 18.60768595
GOTERM_CC_DIRECT GO:0031012~extracellular matrix 4 0.061680802 .032469722 29.89178143
GOTERM_CC_DIRECT GO:0005615~extracellular space 8 0.123361604 .036771948 33.17391345
GOTERM_CC_DIRECT GO:0002080~acrosomal membrane 2 0.030840401 .043912815 38.31524409
GOTERM_MF_DIRECT GO:0016491~oxidoreductase activity 4 0.061680802 .014279333 14.99791487
GOTERM_MF_DIRECT GO:0005215~transporter activity 4 0.061680802 .014662761 15.37073704
GOTERM_MF_DIRECT GO:0004024~alcohol dehydrogenase activity zinc‐dependent 2 0.030840401 .015188693 15.87969632
GOTERM_MF_DIRECT GO:0005372~water transmembrane transporter activity 2 0.030840401 .015188693 15.87969632
GOTERM_MF_DIRECT GO:0008131~primary amine oxidase activity 2 0.030840401 .015188693 15.87969632
GOTERM_MF_DIRECT GO:0015254~glycerol channel activity 2 0.030840401 .030151975 29.24210187
GOTERM_MF_DIRECT GO:0015250~water channel activity 2 0.030840401 .040003884 36.95130237

Abbreviations: DEGs, differentially expressed genes; Go, Gene ontology.