Figure 1.

Pedigrees of two families with autosomal recessive retinitis pigmentosa (ARRP) and pathogenic variations were identified by Sanger sequencing in participants. (a) Pedigrees of two families. Squares represent males and circles represent females; black and white shades represent affected and unaffected individuals, respectively. Black lines indicate deceased individuals, and the probands were marked with an arrow. (b) Sanger sequencing of mutation No.1 (MU1): c.9252_9253insT, Hom and c.9252_9253insT, Het. (c) Sanger sequencing of mutation No.2 (MU2): c.5644+2T>C, Het and wild type. (d) Sanger sequencing of mutation No.3 (MU3): c.1920_1923delTGAG, Het and wild type