Skip to main content
. 2019 Dec 28;8(3):e1107. doi: 10.1002/mgg3.1107

Figure 3.

Figure 3

Analysis of extracardiac anomalies in lztr1 del/del mutants and the target signaling pathways downstream of LZTR1. (a) Vascular malformations could be observed in the lztr1 del/del mutants through the skin as a red coloration. Hematoxylin‐eosin staining of longitudinal sections show the multiple vascular malformations (arrowheads) in the cranial part of the lztr1 del/del mutant. (b) Western blot analysis of heart lysates from control (wild‐type and lztr1 del/+) and lztr1 del/del homozygous mutants detected with the indicated antibodies. No clear differences were obtained in signaling pathway phosphorylation levels