Table 2. Characteristics of Patients in Propensity Score–Adjusted Cohort by CVC Concurrence Status.
| Characteristic | No. (%) | P Valueb | ||
|---|---|---|---|---|
| Total (N = 11 796) | CVC Concurrence (n = 3932)a | No CVC Concurrence (n = 7864) | ||
| CLABSI | 155 (1.3) | 74 (1.9) | 81 (1.0) | .001 |
| Women | 5873 (49.8) | 1917 (48.8) | 3956 (50.3) | .11 |
| Age, median (IQR), y | 59.0 (47-69) | 58 (47-67) | 59 (47-69) | <.001 |
| CCI score, median (IQR) | 5 (3-8) | 5 (3-7) | 5 (3-8) | .18 |
| Receiving chemotherapy | 241 (2.0) | 84 (2.1) | 157 (2.0) | .61 |
| Receiving TPN | 1404 (11.9) | 554 (14.1) | 850 (10.8) | <.001 |
| Receiving hemodialysis | 5118 (43.4) | 1706 (43.4) | 3412 (43.4) | .99 |
| CVC type | ||||
| Port | 2267 (19.2) | 1097 (27.9) | 1170 (14.9) | <.001 |
| PICC | 3545 (30.1) | 1644 (41.8) | 1901 (24.2) | <.001 |
| Otherc | 4233 (35.9) | 2551 (64.9) | 1682 (21.4) | <.001 |
| CLD, median (IQR) | ||||
| NHSNd | 7.0 (4.0-13.0) | 11.0 (6.0-18.0) | 5.0 (3.0-10.0) | <.001 |
| Totale | 8.0 (4.0-16.0) | 17.0 (10.0-28.0) | 5.0 (3.0-10.0) | <.001 |
| NHSN CLD with >1 CVC, median (IQR), %f | 0 (0-40.0) | 66.7 (40.0-93.8) | NA | <.001 |
Abbreviations: CCI, Charlson Comorbidity Index; CLABSI, central line–associated bloodstream infection; CLD, central line–day; CVC, central venous catheter; IQR, interquartile range; NA, not applicable; NHSN, National Health Care Safety Network; PICC, peripherally inserted central catheter; port, implanted central venous catheters requiring percutaneous puncture to access; TPN, total parenteral nutrition.
Concurrence was defined as any 2 CVCs present for 2 or more of the same days.
For categorical variables, P values were calculated using χ2 test; continuous variables with normal distribution, 2-sample t tests; continuous variables with nonnormal distribution, Wilcoxon signed rank tests.
Includes CVC types not listed in the other 3 categories (eg, pulmonary artery catheter, introducer, tunneled CVC, multilumen catheter).
Calculated as 1 day for each day any CVC are present (eg, a patient can contribute a maximum of 1 NHSN CLD per day, regardless of the number of CVCs present).
Calculated as each day for each CVC (eg, a patient with 2 CVCs for 2 days would have 4 total CLD).
Calculated as ([Total CLD / NHSN CLD] / NHSN CLD) × 100 (eg, a patient who had 2 CVCs for their entire CVC experience would have a value of 100%, while a patient who only had 1 CVC at any given time would have a value of 0%).