Table 3. Characteristics of Patients in Propensity Score–Adjusted Cohort by CLABSI Status.
| Characteristic | No (%) | RR (95% CI) | P Value | ||
|---|---|---|---|---|---|
| Total (N = 11 796) | With CLABSI (n = 158) | Without CLABSI (n = 11 638) | |||
| Concurrent CVCsa | 3932 (33.3) | 74 (46.8) | 3858 (33.2) | 1.83 (1.34-2.50) | |
| Women | 5777 (49.0) | 68 (43.0) | 5709 (49.1) | 0.92 (0.67-1.26) | |
| Age, median (IQR), y | 59 (47-68) | 60 (47-67) | 59 (47-68) | NA | .77 |
| CCI score, median (IQR) | 5.0 (3.0-8.0) | 4.0 (2.0-7.0) | 5.0 (3.0-8.0) | NA | .25 |
| Receiving chemotherapy | 241 (2.0) | 9 (5.7) | 232 (2.0) | 2.96 (1.53-5.72) | |
| Receiving TPN | 1404 (11.9) | 31 (19.6) | 1373 (11.8) | 1.81 (1.23-2.67) | |
| Receiving hemodialysis | 5118 (43.4) | 64 (40.5) | 5054 (43.4) | 0.89 (0.65-1.22) | |
| CVC type | |||||
| Port | 2247 (19.0) | 46 (29.1) | 2201 (18.9) | 1.75 (1.24-2.45) | |
| PICC | 3643 (30.9) | 40 (25.3) | 3603 (31.0) | 0.76 (0.53-1.08) | |
| Otherb | 4167 (35.3) | 79 (50.0) | 4088 (35.1) | 1.83 (1.34-2.50) | |
| CLD, median (IQR) | |||||
| NHSNc | 7.0 (4.0-13.0) | 17.0 (9.3-23.8) | 7.0 (4.0-13.0) | NA | <.001 |
| Totald | 8.0 (4.0-16.0) | 21.0 (11.3-33.0) | 8.0 (4.0-16.0) | NA | <.001 |
| NHSN CLD with >1 CVC, median (IQR), % | 0 (0-40.0) | 0 (0-74.1) | 0 (0-40.0) | NA | .001 |
Abbreviations: CCI, Charlson Comorbidity Index; CVC, central venous catheter; CLABSI, central line–associated bloodstream infection; CLD, central line–day; IQR, interquartile range; NA, not applicable; NHSN, National Healthcare Safety Network; PICC, peripherally inserted central catheter; port, port-a-cath; RR, risk ratio; TPN, total parenteral nutrition.
Concurrence was defined as any 2 CVCs present for 2 or more of the same days.
Includes CVC types not listed in the other categories (eg, pulmonary artery catheter, introducer, tunneled CVC, multilumen catheter).
Calculated as 1 day for each day any CVC are present (eg, a patient can contribute a maximum of 1 NHSN CLD per day, regardless of the number of CVCs present).
Calculated as each day for each CVC (eg, a patient with 2 CVCs for 2 days would have 4 total CLDs).