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. 2020 Mar 4;3(3):e200396. doi: 10.1001/jamanetworkopen.2020.0396

Table 4. Multivariable Logistic Regression Output for CLABSI.

Variable Adjusted Risk Ratio (95% CI)
Model 1a Model 2b
NHSN CLD with concurrence, %c
0 1 [Reference] 1 [Reference]
≤66 0.70 (0.48-1.08) 0.58 (0.36-0.92)
>66 1.62 (1.10-2.33) 0.73 (0.45-1.16)
NHSN CLDs, per 1-unit increased 1.08 (1.07-1.10) NA
Total CLDs, per 1-unit increasee NA 1.06 (1.05-1.07)
Age, per 1-y increase 1.00 (0.99-1.01) 1.00 (0.99-1.01)
Male sex 1.36 (0.99-1.89) 1.35 (0.98-1.86)
Propensity scoref 1.23 (0.23-6.24) 1.25 (0.23-6.35)

Abbreviations: CLABSI, central line–associated bloodstream infection; CLD, central line–day; CVC, central venous catheter; NA, not applicable; NHSN, National Healthcare Safety Network.

a

Adjusted for age, sex, propensity score, NHSN CLD, and proportion of NHSN CLD with concurrence (categorized as 0%, ≤66%, or >66%).

b

Adjusted for age, sex, propensity score, total CLD, and proportion of NHSN CLD with concurrence (categorized as 0%, ≤66%, or >66%).

c

Concurrence was defined as any 2 CVCs present for 2 or more of the same days. Percentage of concurrence was calculated as ([total CLD / NHSN CLD] / NHSN CLD) × 100 (median [interquartile range] for patients with concurrent CVCs, 66.7% [40.0%-93.8%]).

d

Calculated as 1 day for each day any CVC is present (ie, a patient can contribute a maximum of 1 NHSN CLD per calendar day, regardless of the number of CVCs present).

e

Calculated as each day for each CVC (eg, a patient with 2 CVCs for for 2 days would be considered to have 4 total CLDs).

f

Calculated as the output of a logistic regression model in which the outcome is any concurrence of CLABSI; the risk factors include Charlson Comorbidity Index score and receipt of hemodialysis, chemotherapy, or total parenteral nutrition.