Table 4: Multivariable model for DFS based on clinical characteristics and baseline CXCL10.

A multivariable model was created to assess the additional predictive value of angiogenic factors and cytokines on DFS with reference to known prognostic factors used in the UISS score, including T-stage, Fuhrman grade, and ECOG performance status (Zisman et al 2002).

	HR	95% CI	p-value
T2 vs. T1	1.30	(0.70, 2.43)	0.41
T3 vs. T1	1.68	(0.95, 2.96)	0.072
T4 vs. T1	1.61	(0.21, 12.48)	0.65
Grade 2 vs. 1	0.91	(0.39, 2.14)	0.83
Grade 3 vs. 1	0.97	(0.42, 2.27)	0.95
Grade 4 vs. 1	1.65	(0.69, 3.94)	0.26
PS ≥ 1 vs. 0	1.16	(0.79, 1.70)	0.45
Baseline CXCL10	1.37	(1.13, 1.67)	0.002