Figure 2.
m6A Methyltransferase METTL3 Indicates the Poor Prognosis of OSCC
(A) Results based on the TCGA (http://software.broadinstitute.org/software/igv/tcga) and GEPIA (http://gepia.cancer-pku.cn/index.html) databases showed the expression level of methyltransferase (METTL3, METTL14), demethyltransferase (ALKBH5, FTO), and reader (YTHDF1, YTHDF2). (B) qRT-PCR illustrated the quantitative analysis of METTL3 and YTHDF1. (C) In the OSCC cells, quantitative analysis of METTL3 was performed by the qRT-PCR. (D) Kaplan-Meier and log-rank testing showed the prognosis of patients in the OSCC patients cohort. Three independent experiments were performed. *p < 0.05 versus control; **p < 0.01 versus control.