Table 3. Association Between Oral and Topical Terbinafine Use in Pregnancy and Risk of the Secondary Outcome Spontaneous Abortions in Matched Cohorts on Propensity Scores.
Spontaneous Abortion | Total No. of Pregnancies | Spontaneous Abortion, No. (%) | Hazard Ratio (95% CI) |
---|---|---|---|
Oral terbinafine-exposed vs unexposed matched pregnancies | |||
Oral terbinafine | 891 | 93 (10.4) | 1.06 (0.86-1.32) |
Unexposed | 8910 | 918 (10.3) | 1 [Reference] |
Topical terbinafine-exposed vs unexposed matched pregnancies | |||
Topical terbinafine | 3174 | 166 (5.2) | 1.04 (0.88-1.21) |
Unexposed | 31 740 | 1607 (5.1) | 1 [Reference] |
Oral vs topical terbinafine-exposed matched pregnancies | |||
Oral terbinafine | 617 | 66 (10.7) | 1.19 (0.84-1.70) |
Topical terbinafine | 617 | 59 (9.6) | 1 [Reference] |