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. 2020 Mar 4;156(4):375–383. doi: 10.1001/jamadermatol.2020.0142

Table 3. Association Between Oral and Topical Terbinafine Use in Pregnancy and Risk of the Secondary Outcome Spontaneous Abortions in Matched Cohorts on Propensity Scores.

Spontaneous Abortion Total No. of Pregnancies Spontaneous Abortion, No. (%) Hazard Ratio (95% CI)
Oral terbinafine-exposed vs unexposed matched pregnancies
Oral terbinafine 891 93 (10.4) 1.06 (0.86-1.32)
Unexposed 8910 918 (10.3) 1 [Reference]
Topical terbinafine-exposed vs unexposed matched pregnancies
Topical terbinafine 3174 166 (5.2) 1.04 (0.88-1.21)
Unexposed 31 740 1607 (5.1) 1 [Reference]
Oral vs topical terbinafine-exposed matched pregnancies
Oral terbinafine 617 66 (10.7) 1.19 (0.84-1.70)
Topical terbinafine 617 59 (9.6) 1 [Reference]