Table 1.
Taxa with increased/decreased abundance in T1D subjects identified in longitudinal human studies. Summary of findings from all longitudinal human studies discussed in this review.
| Phylum | Class | Family | Genus | Species | Study cohort | References |
|---|---|---|---|---|---|---|
| A.TAXA IDENTIFIED IN LONGITUDINAL STUDIES AS INCREASED IN T1D PATIENTS | ||||||
| Actinobacteria | Actinobacteria | Bifidobacteriaceae | Bifidobacterium | pseudocatenulatum | TEDDY | (19) |
| Firmicutes | Clostridia | Lachnospiraceae | Roseburia | hominis | TEDDY | (19) |
| Bacteroidetes | Bacteroidia | Rikenellaceae | Alistepes | shahii | TEDDY | (19) |
| Bacteroidetes | Bacteroidales | Porphyromonadaceae | Parabacteroides | TEDDY | (74) | |
| Firmicutes | Bacilli | Streptococcaceae | Streptococcus | DIABIMMUNE | (75) | |
| Firmicutes | Clostridia | Lachnospiraceae | Blautia | DIABIMMUNE | (75) | |
| Firmicutes | Clostridia | Ruminococcaceae | Ruminococcus | DIABIMMUNE | (75) | |
| Bacteroidetes | Bacteroidia | Bacteroidaceae | Bacteroides | DIABIMMUNE, FINDIA | (76, 77) | |
| B.TAXA IDENTIFIED IN LONGITUDINAL STUDIES AS DECREASED IN T1D PATIENTS | ||||||
| Firmicutes | Clostridia | Ruminococcaceae | TEDDY | (74) | ||
| Firmicutes | Bacilli | Streptococcaceae | Lactococcus | TEDDY | (74) | |
| Firmicutes | Bacilli | Streptococcaceae | Streptococcus | TEDDY | (74) | |
| Verrucomicrobia | Verrucomicrobiae | Verrucomicrobiaceae | Akkermansia | DIABIMMUNE | (75) | |
| Firmicutes | Negativicutes | Veillonellaceae | DIABIMMUNE | (75) | ||