Conventional μCT confirms that concurrent disuse rescues the age-dependent reduced loading response in old male mice. Conventional μCT analysis of (A) periosteally enclosed (Tt.Ar), (B) cortical area (Ct.Ar), (C) polar moment of inertia (PMI), (D) trabecular bone volume (BV/TV), (E) trabecular thickness (Tb.Th) and (F) structure model index (SMI) are shown for sham and neurectomized (SN) mice. Left non-loaded tibiae are represented by white boxes and right loaded tibiae are indicated by black boxes. N = 13 for sham and N = 12 for SN. *p < 0.05, **p < 0.01, ***p < 0.001 comparing right and paired left limbs. #p < 0.05, ##p < 0.01 comparing the percentage change due to loading between Sham and SN mice.