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. 2020 Feb 25;10:189. doi: 10.3389/fonc.2020.00189

Table 3.

Papers showing a prognostic value of extended genotyping in newly diagnosed myeloma.

Study Method of detection What detected
Palumbo et al. (46) FISH t(4:14), t(14;16), del(17p)
Carballo-Zarate et al. (49) Karyotype, FISH (HDMM patients only) del(1p), amp(1q), t(11;14), del(13q), del(17p)
Bolli et al. (21) Targeted 197 different events (mutations, CNAs, translocations)
Maura et al. (95) WES Mutational signatures
Walker et al. (22) WES Any driver gene mutation
Walker et al. (98) WES TP53 mutations, amp(1q), t(4:14), t(14;16), del(17p)
Perrot et al. (50) FISH, Cytoscan HD arrays Trisomy 5, Trisomy 21, t(4;14), amp(1q), del(1p32), del(17p)
Barwick et al. (105) WGS IGL translocations