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Interaction kinetic analysis of linear H31-11 K4M peptide variants with immobilized LSD1. (A) H31-11 K4M (peptide 4), (B) wild-type K4 (peptide 9), (C) A1P-substituted H31-11 K4M (peptide 11), and (D) Ala1 to tert-leucine-substituted H31-11 K4M (peptide 12) dilution series from 100 μM. Insets correspond to interaction isotherms, fitted with the Langmuir model (red lines).
