Figure 1.
Spinal radiographic progression over time in patients with AS and nr-axSpA.
The figure shows mean mSASSS progression at baseline in TNFi-treated (solid lines) and TNFi-untreated (dashed lines) patients with AS and nr-axSpA. Reasons for excluding data from this figure were: median rather than mean mSASSS data were reported (Pedersen et al.;40 Beek et al.47) or increases in mSASSS for individual populations were not reported (Molnar et al.;6 Park et al.46). For studies that reported mSASSS change from baseline, absolute mSASSS at follow-up was calculated using the reported data. Both absolute and mean follow-up times are shown in the figure, depending on which were reported in the study. For further details on reported follow-up intervals, see Table 1.
AS, ankylosing spondylitis; mSASSS, modified Stoke Ankylosing Spondylitis Spine Score; nr-axSpA, nonradiographic axial spondyloarthritis; NSAIDs, nonsteroidal anti-inflammatory drugs; TNFi, tumor necrosis factor inhibitor.