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. 2020 Feb 10;8(1):e000110. doi: 10.1136/jitc-2019-000110

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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The tumor-infiltrating immune-related lncRNA signature (TILSig) is associated with outcome and immune cell infiltrates. (A) Kaplan-Meier survival curves of overall survival between patients with a higher score of TILSig and with the lower score of TILSig. (B) Time-dependent receiver operating characteristic (ROC) curve at 5 and 3 years of overall survival (OS). (C) The distribution of TILSig, patients’ survival status and long non-coding RNA (lncRNA) expression pattern. (D) Volcano plots for the enrichment of immune cell types for tumors with high TILSig and low TILSig calculated based on the NES score from the gene set enrichment analysis (GSEA). AUC, area under the curve; NES, normalized enrichment scores; NK, natural killer; NKT, natural killer T cell.