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. 2020 Feb 24;8(1):e000131. doi: 10.1136/jitc-2019-000131

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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CCL5-expressing vaccinia virus augmented NK-CCR5 cell therapy. As depicted in figure 6, mice inoculated with HCT-116 cells received the indicated treatments. (A, B) Tumor growth (A) and mouse survival (B) were monitored separately. The number and median survival time (days) of mice from different groups are indicated in corresponding plots. Kaplan-Meier curves and log-rank tests were used to estimate and compare survival, respectively, followed by Bonferroni correction. *P<0.05, **P<0.01, ***P<0.005. n.s. indicates no significant difference; NK, natural killer; OV, oncolytic viruse; PFU, plaque-forming unit.