Table 5.

Sensitivity, specificity, PPV, and NPV at optimal cutoffs with AUC regarding tumor size (2.1–3 cm)

Gene	Sensitivity	Specificity	PPV	NPV	AUC	95% CI
CDO1	67%	89%	94%	53%	0.77	0.64–0.90
TAC1	65%	72%	85%	46%	0.67	0.51–0.83
SOX17	67%	90%	94%	53%	0.79	0.68–0.90
HOXA7	70%	83%	91%	54%	0.77	0.65–0.89
CDO1, TAC1, SOX17	88%	89%	95%	76%	0.91	0.83–0.99
CDO1, SOX17, HOXA7	91%	90%	96%	81%	0.95	0.90–1.00

Cancer, n = 43; control, n = 18