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. 2020 Mar 5;20:47. doi: 10.1186/s12876-020-01196-0

Table 4.

Sustained Virologic Response Rates (95% Confidence Intervals) in Patients infected with HCV Genotype 2, 4, and 6

Genotype 2 SVR, % (95% CI) Genotype 4 SVR, % (95% CI) Genotype 6 SVR, % (95% CI)
All patients DAC + SOF SOF/VEL All patients LDV/SOF DAC + SOF All patients LDV/SOF DAC + SOF SOF/VEL
Patients who complete, N 14 10 4 11 1 10 152 36 109 7
 All durations 100 (78.5–100) 100 (72.2–100) 100 (51.0–100) 90.9 (62.3–98.4) 100 (20.7–100) 90.0 (59.6–98.2) 96.7 (92.5–98.6) 97.2 (85.8–99.5) 96.3 (90.9–98.6) 100 (64.6–100)
 12-wk treatment 100 (77.2–100) 100 (70.1–100) 100 (51.0–100) 87.5 (52.9–97.8) 100 (20.7–100) 85.7 (48.7–97.4) 97.1 (92.9–98.9) 97.0 (84.7–99.5) 97.0 (91.5–99.0) 100 (64.6–100)
 16-wk treatment NA NA NA NA NA NA 100 (34.2–100) NA 100 (34.2–100) NA
 24-wk treatment 100 (20.7–100) 100 (20.7–100) NA 100 (43.9–100) NA 100 (43.9–100) 90.0 (59.6–98.2) 100 (43.9–100) 85.7 (48.7–97.4) NA
SVR in the following subgroups
 No cirrhosis 100 (74.1–100) 100 (64.6–100) 100 (51.0–100) 100 (61.0–100) 100 (20.7–100) 100 (56.6–100) 96.8 (90.9–98.9) 100 (82.4–100) 95.8 (88.5–98.6) 100 (43.9–100)
 Cirrhosis 100 (43.9–100) 100 (43.9–100) NA 80.0 (37.6–96.4) NA 80.0 (37.6–96.4) 96.6 (88.5–99.1) 94.4 (74.2–99.0) 97.3 (86.2–99.5) 100 (51.0–100)
 Decompensated cirrhosis 100 (20.7–100) 100 (20.7–100) NA 100 (20.7–100) NA 100 (20.7–100) 100 (67.6–100) 100 (34.2–100) 100 (56.6–100) 100 (20.7–100)
 Treatment-naive 100 (75.8–100) 100 (67.6–100) 100 (51.0–100) 83.3 (43.6–97.0) NA 83.3 (43.6–97.0) 99.1 (94.8–99.8) 100 (88.6–100) 98.6 (92.3–99.7) 100 (61.0–100)
 Treatment-experienced 100 (34.2–100) 100 (34.2–100) NA 100 (56.6–100) 100 (20.7–100) 100 (51.0–100) 91.3 (79.7–96.6) 83.3 (43.6–97.0) 92.3 (79.7–97.3) 100 (20.7–100)