Table 2.
Statistical analysis of cell populations in the peripheral blood
| Cell populations compared | Group A | Group B | Group C | p value |
|---|---|---|---|---|
| % MN-RET | 1.3 (1–1.6) | 2.7 (2.1–3.4) | 0.7 (0.4–1.3) |
B vs C p = 0.002 A vs C p = 0.07 |
| B cell populations | ||||
| % B cells CD19+ | 10.5 (7.4–14.4) | 10.3 (5.85–12.4) | 8.4 (6.7–9.7) |
B vs C p = 0.4 A vs C p = 0.1 |
|
% B cells naive CD19+CD27-IgD+ |
58 (53.5–62.6) | 64.5 (58–70.9) | 54.6 (46.2–59.2) |
B vs C p = 0.01 A vs C p = 0.4 |
|
% B cells Class-switched memory CD19+ IgD-IgM- CD38-CD27+ |
15 (11.1–20.6) | 12.8 (10.5–14) | 19 (16.8–21.4) |
B vs C p = 0.001 A vs C p = 0.06 |
|
% B cells Class-unswitched memory CD19+ IgD+IgM+CD38-CD27+ |
18.7 (14.5–23.3) | 15.4 (11.8–18.5) | 22.6 (20.1–25.8) |
B vs C p = 0.002 A vs C p = 0.05 |
| T cell populations | ||||
| % T cells CD3+ | 62(53.5–75.1) | 75.3(56.3–79.6) | 76.8(60.1–82.1) |
B vs C p = 0.6 A vs C p = 0.4 |
| % T cells CD4+ | 62.7(59.9–67.2) | 61.8(53.4–67.2) | 57.5(55–65) |
B vs C p = 0.6 A vs C p = 0.4 |
| % T cells CD8+ | 30(24–31.6) | 30.7(24.6–35.3) | 32.1(28.6–35) |
B vs C p = 0.5 A vs C p = 0.1 |
| % T cells CD4+PD1+ | 20.5(13.1–29.7) | 29.7(26.7–30.5) | 23.5(13.1–25.6) |
B vs C p = 0.05 A vs C p = 0.8 |
| % T cells CD8+PD1+ | 22.6(18.9–27.9) | 30 (28.3–32.9) | 19.3(16.3–26.1) |
B vs C p = 0.008 A vs C p = 0.3 |
| % Naive-T cells CD4+CCR7+CD45RA+ | 26.9(20.6–37.4) | 37.1(31.6–48.2) | 27.3 (24–39.4) |
B vs C p = 0.2 A vs C p = 0.6 |
| % effector memory T cells CD4+CCR7−CD45RA− | 22.7 (14.5–29.3) | 15.8(11.1–25.7) | 22.2(14.9–24.7) |
B vs C p = 0.4 A vs C p = 0.6 |
| % central memory T cells CD4+CCR7+CD45RA- | 48.6 (42.5–55.8) | 42(34.1–43.2) | 46.5(40.1–58.2) |
B vs C p = 0.1 A vs C p = 0.7 |
Group A: Autotransplantation splenic tissue
Group B: Splenectomy
Group C: Healthy volunteers
Values are expressed as median (25th and 75th percentiles)