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. 2020 Mar 4;13:32. doi: 10.1186/s12920-020-0671-8

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Error-corrected sequencing noise reduction for low allelic variants. Top panel represents all variants (blue dots) identified in the genomic region of a known somatic mutation located in PTPN11 (red dot). Bottom panel demonstrates noise reduction with the application of error-corrected sequencing