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. 2020 Mar 4;13:11. doi: 10.1186/s13047-020-0379-1

Fig. 1.

Fig. 1

Manhattan plot represents the p-values of the entire GWAS on genomic scale. The p-values are ordered by chromosome and position on the corresponding chromosome (x-axis). The value on the y-axis is the (–log10) of the p-value and is equivalent to the number of zeros after the decimal point plus one. The graph looks like a Manhattan skyline because of local correlation of SNPs. The red line shows the threshold for genome-wide significance