Table 4.
Most common mmedications requiring dose adjustment or precautions, defined by the CG equation
| Category | Medications | Patients (%) |
|---|---|---|
| dose modification is recommended based on ClCr | Allopurinol | 167 (30) |
| Atenolol | 34 (6.1) | |
| Acebutolol | 31 (5.6) | |
| Lorazepama | 31 (5.6) | |
| Hydroxyzinea | 27 (4.9) | |
| Perindopril | 20 (3.6) | |
| Bromazepama | 17 (3.1) | |
| Tianeptine | 15 (2.7) | |
| dose modification based on CrCl is not recommanded but a maximum daily dose is mentionned | Ramipril | 70 (12.6) |
| Nebivolol | 56 (10.1) | |
| Simvastatin | 37 (6.7) | |
| no specific recommendations | Bisoprolol | 93 (16.7) |
| Clopidogrel | 91 (16.4) | |
| Fluindione | 72 (12.9) | |
| Pravastatin | 53 (9.5) | |
| Repaglinide | 35 (6.1) | |
| Candesartan | 31 (5.6) | |
| Warfarin | 15 (2.7) | |
| Clonazepam | 14 (2.5) | |
| Celiprolol | 14 (2.5) |
CrCl Creatinine clearance
aLorazepam, Hydroxyzine and Bromazepam are both Renally Inappropriate Medications (RIM) and Potentially Inappropriate-for-the-elderly Medication (PIM)