Table 4.
First | Second | Third | Fourth | P-valuea | P-value trend testb | P-value adjustedc | |
---|---|---|---|---|---|---|---|
N | 333 | 330 | 326 | 329 | |||
Interleukin 6, median [IQR] | 0.41 [0.22–0.63] | 1.52 [1.19–1.87] | 3.84 [2.98–5.30] | 22.01 [12.33–61.31] | |||
Traumatic fracture (%) | 76 (22.8) | 99 (30.0) | 80 (24.5) | 91 (27.6) | 0.155 | 0.497 | |
Major osteoporotic fracture (%) | 32 (9.61) | 39 (11.82) | 36 (11.04) | 35 (10.64) | 0.832 | 0.997 | |
Incident fracture 5 years | 20/323 (6.2) | 12/320 (3.7) | 21/318 (6.6) | 22/323 (6.8) | 0.320 | 0.461 | |
Spine average BMD | 0.921 ± 0.168 | 0.932 ± 0.164 | 0.933 ± 0.155 | 0.915 ± 0.168 | 0.437 | 0.696 | 0.375 |
Spine average T-score | −1.13 ± 1.59 | −1.03 ± 1.54 | −1.01 ± 1.46 | −1.18 ± 1.58 | 0.424 | 0.707 | 0.367 |
Spine average TBS | 1.322 ± 0.104 | 1.326 ± .0105 | 1.319 ± 0.103 | 1.319 ± 0.098 | 0.773 | 0.509 | 0.525 |
Femoral neck BMD | 0.724 ± 0.113 | 0.727 ± 0.114 | 0.741 ± 0.112 | 0.727 ± 0.199 | 0.234 | 0.424 | 0.391 |
Femoral neck T-score | −1.13 ± 1.01 | −1.096 ± 1.02 | −0.97 ± 1.00 | −1.10 ± 1.07 | 0.223 | 0.397 | 0.361 |
Femur total BMD | 0.848 ± 0.118 | 0.857 ± 0.121 | 0.869 ± 0.119 | 0.845 ± 0.112 | 0.046 | 0.945 | 0.979 |
Femur total T-score | −0.77 ± 0.96 | −0.69 ± 0.98 | − 0.59 ± 0.97 | −0.79 ± 0.92 | 0.043 | 0.913 | 0.987 |
Results are expressed as number of participants (%) or as mean ± standard deviation. Statistical analysis performed using chi-square for categorical variables and ANOVA for continuous variablesa, p of trendb and after multiple adjustmentc (age, BMI, smoker, diabetes, alcohol, calcium, HRT)