Table II.
Clinicopathological variables of patients with Kawasaki disease categorized according to the serum anti-HSP7C antibody expression status.
| A, Laboratory variables | |||
|---|---|---|---|
| Serum anti-HSP7C antibody level | |||
| Variable | Low (n=20) | High (n=30) | P-value |
| Sex (female/male) | 9/11 | 13/17 | 0.9074 |
| Age (years)a | 2.6±2.2 | 2.4±2.3 | 0.7165 |
| Neutrophil granulocyte %a | 52.5±24.6 | 52.7±22.9 | 0.9658 |
| C-reactive protein (mg/l)a | 53.0±60.5 | 57.7±49.8 | 0.7640 |
| Erythrocyte sedimentation rate (mm/h)a | 63.5±31.4 | 60.2±29.6 | 0.7118 |
| White blood cell (109/l)a | 11.2±4.4 | 11.0±5.1 | 0.9037 |
| Red blood cell (1012/l)a | 4.7±0.3 | 3.9±0.3 | 0.1268 |
| Hemoglobin (g/l)a | 107.3±12.8 | 103.1±7.7 | 0.2018 |
| Blood platelet (109/l)a | 461.6±128.0 | 355.5±140.8 | 0.0094 |
| B, Clinical variables | |||
| Serum anti-HSP7C antibody level | |||
| Variable | Low (n=20) | High (n=30) | P-value |
| Coronary artery lesions (−/+) | 13/7 | 26/4 | 0.0700 |
| Fever (−/+) | 1/19 | 0/30 | 0.2160 |
| Lymph nodes (−/+) | 2/18 | 3/27 | >0.9999 |
| Bilateral conjunctival hyperemia (−/+) | 1/19 | 1/29 | 0.7683 |
| Lips red and chapped (−/+) | 2/18 | 1/29 | 0.3308 |
| Hard swelling of hands and feet (−/+) | 5/15 | 8/22 | 0.8953 |
| Torsal polymorphic erythema (−/+) | 15/5 | 13/17 | 0.0271 |
a
Data are presented as the mean ± SD. FC, non-KD febrile control; HC, healthy control; high group, ELISA cut-off value >0.267; HSP7C, heat shock cognate 71 kDa protein; KD, Kawasaki disease; low group, ELISA cut-off value ≤0.267.