Table III.
Relationship between miR-34a expression and clinicopathological features in CRC patients.
| miR-34a | ||||
|---|---|---|---|---|
| Characteristics | n | Low | High | P-value |
| Age (years) | 0.603 | |||
| <60 | 27 | 14 | 13 | |
| ≥60 | 33 | 16 | 17 | |
| Sex | 0.397 | |||
| Male | 26 | 14 | 12 | |
| Female | 34 | 16 | 18 | |
| Tumor size (cm) | 0.094 | |||
| <5 | 36 | 19 | 17 | |
| ≥5 | 24 | 11 | 13 | |
| Differentiation | <0.001 | |||
| Well/moderate | 20 | 2 | 18 | |
| Poor | 40 | 28 | 12 | |
| Lymphatic node metastasis | <0.001 | |||
| Present | 43 | 28 | 15 | |
| Absent | 17 | 2 | 15 | |
| Clinical stages | <0.001 | |||
| I/II | 17 | 2 | 15 | |
| III/IV | 43 | 28 | 15 | |
| CA199 level (U/ml) | 0.500 | |||
| <37 | 31 | 15 | 16 | |
| ≥37 | 29 | 15 | 14 | |
| CEA level (ng/ml) | <0.001 | |||
| <5 | 16 | 2 | 14 | |
| ≥5 | 44 | 28 | 16 | |
The median value of miR-34a expression level in CRC patients was 0.6725. P<0.05 is considered to indicate a statistically significant difference. CRC, colorectal cancer; CA, carbohydrate antigen; CEA, carcinoembryonic antigen.