Figure 1.

Common sources of cytomegalovirus (CMV) for seronegative women and implications for sample collection and clinical trial design. By analogy with transplant patients at risk of CMV infection, family members are considered as donors of virus for the female recipient. Gray represents uninfected and red represents infected. Collection and storage of serial samples from all family members is envisaged as part of clinical trial design. This would allow the strain of CMV causing congenital infection to be formally linked with the strain in the donor.