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LiCl reverses the inhibitory effect of APS on the Wnt/β-catenin signaling pathway. MCF-7 and MDA-MB-231 cells were cultured with LiCl (10 mM) and 800 µg/ml APS. Protein expression levels of β-catenin, Snail, vimentin, E-cadherin, c-Myc and Cyclin D1 were (A) determined by western blotting and (B) quantified. *P<0.05 and **P<0.01 vs. the respective control group; #P<0.05 and ##P<0.01 vs. the APS group. LiCl, lithium chloride; APS, Astragalus polysaccharide; CON, control.
