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. 2020 Jan 31;21(4):1910–1920. doi: 10.3892/mmr.2020.10970

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Copyright: © Zong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — AIF knockdown attenuated mitochondrial respiratory functions and ATP generation. Specific activities of mitochondrial (A) complex I (rotenone-sensitive NADH-ubiquinone oxidoreductase) (n=12), (B) complex II/III (succinate-cytochrome c oxidoreductase) (n=12), (C) complex IV (cytochrome c oxidase) (n=12) and (D) ATP generation (n=12). (E) Flow cytometry results by MitoProbe™ DiIC1 detection of mitochondrial membrane potential. *P<0.05 and **P<0.01 vs. TCPS and siRNA-control. ATP, adenosine triphosphate.