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. 2020 Feb 12;43(4):1159–1168. doi: 10.3892/or.2020.7498

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effects of Tan IIA on the proliferation of HCT-116 under hypoxic conditions. The effects of Tan IIA on proliferation of HCT-116 cell proliferation was analyzed using a Cell Counting Kit-8 assay under (A) normal and (B) hypoxic conditions. Tan IIA was used at a concentration of 2, 4, 8, 16, 32 and 64 µM under normal conditions, and 1, 5, 10, 15, 20 and 25 µM under hypoxic. IC₅₀ was analyzed in cells treated for 24, 48 and 72 h under (C) normal and (D) hypoxic conditions. **P<0.01 vs. 24 h. Tan IIA, tanshinone IIA.