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. 2020 Feb 12;43(4):1208–1220. doi: 10.3892/or.2020.7499

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Copyright: © Bai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — MiD49 suppresses the growth and metastasis of pancreatic cancer (PC) cells in vivo. (A) MiD49 expression was determined by qPCR and western blot analyses in SW1990 cells (MiD49, expression vector encoding MiD49; EV, empty vector). (B) Tumor growth curves of the two groups of MiD49 and EV are shown. (C) Harvested tumors and their weights were compared between the two groups. Scale bar, 1 cm. (D) The expression level of MiD49 was determined by immunohistochemical (IHC) staining in tumor tissues from the two groups of MiD49 and EV. Scale bars, 10 µm. (E) Ki-67 staining by IHC analysis in tumor tissues from the two groups of MiD49 and EV. Scale bars, 10 µm. (F) Incidence of pulmonary metastasis in the two groups of MiD49 and EV. MiD49, mitochondrial dynamics protein of 49 kDa. *P<0.05.