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. 2020 Mar 5;10:4139. doi: 10.1038/s41598-020-60659-2

Table 1.

Risk factors of acquiring IMP-6 carbapenemase-producing Enterobacterales among cases with abdominal surgery, Osaka, Japan, 2013–2014.

Factors Case (%) Median Control (%) Median OR 95%CI p aOR* 95%CI p
n = 11 (IQR) n = 24 (IQR)
Age, years old 76 (65–78) 71 (65–77.5) 0.44 0.32
Male gender 9 (82) 15 (63) 2.7 (0.4–30.4) 0.44 2.5 (0.4–14.5) 0.31
ASA score 2 (2–2) 2 (2–2.5) 0.22 0.11
Diabetes mellitus 1 (9) 2 (8) 1.1 (0.0–23.5) 1.00 1.0 (0.1–12.3) 0.99
Endoscopy within the past 6 months 8 (73) 18 (75) 0.9 (0.1–6.9) 1.00 0.8 (0.2–4.2) 0.81
Room share with cases 7 (64) 10 (42) 2.5 (0.5–14.4) 0.29 2.2 (0.5–10.0) 0.30
ICU admission 9 (82) 16 (67) 2.3 (0.3–25.7) 0.45 2.6 (0.4–17.0) 0.32
ICU admission days 2 (1–4) 1 (0–3.5) 0.34 0.33
Pancreato-duodenectomy 6 (55) 4 (17) 6.0 (0.9–40.0) 0.04 6.4 (1.3–32.4) 0.03
Surgical site infection 11 (100) 19 (79) (0.7 −) 0.16
Changing drains at fluoroscopy room 11 (100) 13 (54) (2.2 −) <0.01
Continuous peritoneal lavage 9 (82) 10 (42) 6.3 (0.9–68.6) 0.04 5.9 (1.0–34.8) 0.05
Arterial line 11 (100) 19 (80) (0.7 −) 0.16
Central venous line 10 (91) 15 (63) 6.0 (0.6–288.8) 0.12 5.4 (0.6–51.1) 0.14
Enteric fistula 7 (64) 5 (21) 6.7 (1.1–43.1) 0.02 8.0 (1.5–41.9) 0.01
Stoma 1 (9) 10 (42) 0.1 (<0.1–1.3) 0.11 0.2 (<0.1–1.4) 0.10
Enteral feeding 6 (55) 8 (33) 2.4 (0.4–13.2) 0.28 2.6 (0.6–11.4) 0.22
Carbapenem use 2 (18) 10 (42) 0.3 (<0.1–2.1) 0.26 0.3 (0.1–1.8) 0.19
Number of cultures 7.0 (4–9) 7.5 (4.5–11.5) 0.37
Days of hospitalization 20 (6–26) 17 (6–34.5) 0.80

*Adjusted by days of hospitalization.

The univariate analyses of these variables were conducted by conditional logistic regression.

IQR: interquartile range; CI: confidence interval; QR: odds ratio; aOR: adjusted odds ratio; ASA: American Society of Anesthesiology; ICU: intensive care unit.