Table 3.
Predicted GO terms for all genes in the “saddlebrown” module of the glioma dataset.
Term | Average Z-Score | Description | Genes in Module Predicted for GO Term | Total Number of Human Genes Annotated to GO Term |
---|---|---|---|---|
GO:0022010 | 7.58 | central nervous system myelination | 24 | 33 |
GO:0032291 | 5.47 | axon ensheathment in central nervous system | 24 | 33 |
GO:0016188 | 5.33 | synaptic vesicle maturation | 12 | 24 |
GO:0006559 | 6.09 | L-phenylalanine catabolic process | 12 | 23 |
GO:1902222 | 6.15 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process | 11 | 23 |
GO:0035641 | 5.40 | locomotory exploration behavior | 9 | 25 |
GO:0030497 | 6.24 | fatty acid elongation | 8 | 25 |
GO:0048172 | 5.20 | regulation of short-term neuronal synaptic plasticity | 7 | 27 |
GO:0071625 | 4.75 | vocalization behavior | 6 | 30 |
GO:0006558 | 6.36 | L-phenylalanine metabolic process | 6 | 11 |
GO:1902221 | 6.15 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process | 6 | 21 |
GO:2000463 | 4.78 | positive regulation of excitatory postsynaptic potential | 5 | 35 |
GO:0008366 | 5.46 | axon ensheathment | 5 | 145 |
ARCHS4 predictions were generated for each gene and the top five, ranked by z-score, were selected as possible annotations. Central nervous system myelination and phenylalanine catabolic process were predicted for 24 and 12 of the genes, respectively.