Table 1.
Number of patients per site and characteristics of enrolled TB DOTS patients.
| Metro Manila region (N = 338) | Negros Occidental region (N = 299) | Total (N = 637) | p-value1 | ||
|---|---|---|---|---|---|
| Centre | San Nicolas | 108 | |||
| Pedro Gil | 102 | ||||
| San Lazaro Hospital | 128 | ||||
| Bago City | 222 | ||||
| Valladolid | 77 | ||||
| Sex | Female | 97 (28.7) | 94 (31.4) | 191 (30.0) | 0.488 |
| Male | 241 (71.3) | 205 (68.6) | 446 (70.0) | ||
| Age (years) | 18–40 | 183 (54.1) | 89 (29.8) | 272 (42.7) | <0.001 |
| 41–65 | 127 (37.6) | 154 (51.5) | 281 (44.1) | ||
| >65 | 28 (8.3) | 56 (18.7) | 84 (13.2) | ||
| Household size | mean (SD) | 4.7 (3.1) | 4.7 (2.2) | 4.7 (2.7) | 0.972 |
| Marital status | Single | 171 (50.6) | 87 (29.1) | 258 (40.5) | <0.001 |
| Married | 132 (39.1) | 165 (55.2) | 297 (46.6) | ||
| Divorced/separated | 8 (2.4) | 6 (2.0) | 14 (2.2) | ||
| Widowed | 27 (8.0) | 41 (13.7) | 68 (10.7) | ||
| Highest level of education obtained | Primary | 63 (18.6) | 155 (51.8) | 218 (34.2) | <0.001 |
| Secondary | 147 (43.5) | 104 (34.8) | 251 (39.4) | ||
| Tertiary | 120 (35.5) | 27 (9.0) | 147 (23.1) | ||
| Vocational | 8 (2.4) | 13 (4.3) | 21 (3.3) | ||
| Health insurance2 | No | 145 (45.7) | 98 (33.2) | 243 (39.7) | 0.002 |
| Yes | 172 (54.3) | 197 (66.8) | 369 (60.3) | ||
| Time to health clinic (minutes), median (range) | 15 (0–300) | 6 (1–120) | 10 (0–300) | <0.001 | |
| Smoking status | No or Ex | 304 (89.9) | 209 (69.9) | 513 (80.5) | <0.001 |
| Yes | 34 (10.1) | 90 (30.1) | 124 (19.5) | ||
| Alcohol consumption | Daily | 25 (7.4) | 92 (30.8) | 117 (18.4) | <0.001 |
| Weekly or monthly | 78 (23.1) | 61 (20.4) | 139 (21.8) | ||
| Rarely/Never | 235 (69.5) | 146 (48.8) | 381 (59.8) | ||
| Weight change last 3–6 months3 | No change | 70 (20.8) | 32 (10.7) | 102 (16.0) | <0.001 |
| Increase | 73 (21.7) | 18 (6.0) | 91 (14.3) | ||
| Decrease | 194 (57.6) | 249 (83.3) | 443 (69.7) | ||
| Food intake last 1 month3 | No change | 196 (58.2) | 43 (14.4) | 239 (37.6) | <0.001 |
| Increase | 66 (19.6) | 79 (26.4) | 145 (22.8) | ||
| Moderate decrease | 65 (19.3) | 98 (32.8) | 163 (25.6) | ||
| Severe decrease | 10 (3.0) | 79 (26.4) | 89 (14.0) | ||
| Household Food security score | Secure | 218 (64.5) | 108 (36.1) | 326 (51.2) | <0.001 |
| Moderate insecurity | 69 (20.4) | 98 (32.8) | 167 (26.2) | ||
| Severe insecurity | 51 (15.1) | 93 (31.1) | 144 (22.6) | ||
| Multi-drug resistant TB | No | 305 (90.2) | 299 (100.0) | 604 (94.8) | <0.001 |
| Yes | 33 (9.8) | 0 (0) | 33 (5.2) | ||
| Previous TB4 | New case | 206 (61.5) | 187 (62.8) | 393 (62.1) | 0.806 |
| Relapse case | 129 (38.5) | 111 (37.3) | 240 (37.9) | ||
| Bacteriologically confirmed TB5 | No | 198 (60.2) | 210 (70.2) | 408 (65.0) | 0.009 |
| Yes | 131 (39.8) | 89 (29.8) | 220 (35.0) | ||
| Treatment phase6 | Intensive | 199 (58.9) | 133 (44.5) | 332 (52.1) | <0.001 |
| Continuation | 139 (41.1) | 166 (55.5) | 305 (47.9) | ||
Data are n (%) of non-missing values for each characteristic, unless otherwise indicated as mean (SD) or median (range).
1p-value from Fishers exact test for categorical variables, t-test to compare means or Wilcoxon rank sum test to compare medians.
221 missing values in Metro Manila region and 4 missing values in Negros Occidental region.
31 missing value in Metro Manila region.
43 missing value in Metro Manila and 1 missing value in Negros Occidental region.
59 missing values in Metro Manila region.
6Intensive treatment phase, unless extended, is the first 2 months of the 6 month standard TB-DOTS shorter regimen comprising isoniazid, rifampicin, pyrazinamide and ethambutol, followed by continuation phase comprising isoniazid and rifampicin only. The intensive phase of the 9/12 months WHO shorter regimen for multi-drug resistant TB is the first 4 months (unless extended) comprising kanamycin, moxifloxacin, prothionamide, clofazimine, pyrazinamide and high dose isoniazid and ethambutol followed by continuation phase comprising moxifloxacin, clofazimine, pyrazinamide and ethambutol only.