Table 2.
Prevalence of co-morbidities amongst enrolled TB DOTS patients.
| Characteristic | Metro Manila Region (N = 338) | Negros Occidental Region (N = 299) | Total | p-value1 | |
|---|---|---|---|---|---|
| Undernutrition2 | None or mild | 280/336, 83.3% (78.9–87.2%) | 224/298, 75.2% (69.9–80.0%) | 504/634, 79.5% (76.1–82.6%) | 0.014 |
| Moderate or severe | 56/336, 16.7% (12.8–21.1%) | 74/298, 24.8% (20.0–30.1%) | 130/634, 20.5% (17.4–23.9%) | ||
| Undernutrition2 | None | 228/336, 67.9% (62.6–72.8%) | 174/298, 58.4% (52.6–64.0%) | 402/634, 63.4% (59.5–67.2%) | 0.048 |
| Mild | 52/336, 15.5% (11.8–19.8%) | 50/298, 16.8% (12.7–21.5%) | 102/634, 16.1% (13.3–19.2%) | ||
| Moderate | 22/336, 6.5% (4.1–9.7%) | 33/298, 11.1% (7.7–15.2%) | 55/634, 8.7% (6.6–11.1%) | ||
| Severe | 34/336, 10.1% (7.1–13.9%) | 41/298, 13.8% (10.1–18.2%) | 75/634, 11.8% (9.4–14.6%) | ||
| Diabetes3 | No | 299/325, 92.0% (88.5–94.7%) | 236/264, 89.4% (85.0–92.8%) | 535/589, 90.8% (88.2–93.0%) | 0.316 |
| Yes | 26/325, 8.0% (5.3–11.5%) | 28/264, 10.6% (7.2–15.0%) | 54/589, 9.2% (7.0–11.8%) | ||
| Anaemia4 | None or mild | 297/336, 88.4% (84.5–91.6%) | 249/296, 84.1% (79.5–88.1%) | 546/632, 86.4% (83.5–89.0%) | 0.131 |
| Moderate or severe | 39/336, 11.6% (8.4–15.5%) | 47/296, 15.9% (11.9–20.5%) | 86/632, 13.6% (11.0–16.5%) | ||
| HIV5 | No | 229/303, 75.6% (70.3–80.3%) | 39/41 | – | |
| Yes | 74/303, 24.4% (19.7–29.7%) | 2/41 | |||
| Reported hypertension | No | 312/338, 92.3% (88.9–94.9%) | 270/299, 90.3% (86.4–93.4%) | 582/637, 91.4% (88.9–93.4%) | 0.398 |
| Yes | 26/338, 7.7% (5.1–11.1%) | 29/299, 9.7% (6.6–13.6%) | 55/637, 8.6% (6.6–11.1%) | ||
| Reported chronic obstructive pulmonary disease | No | 338/338, 100.0% (98.9–100.0%) | 296/299, 99.0% (97.1–99.8%) | 634/637, 99.5% (98.6–99.9%) | 0.103 |
| Yes | 0/338, 0.0% (0.0–1.1%) | 3/299, 1.0% (0.2–2.9%) | 3/637, 0.5% (0.1–1.4%) | ||
| Reported Chronic kidney disease | No | 336/338, 99.4% (97.9–99.9%) | 298/299, 99.7% (98.2–100.0%) | 634/637, 99.5% (98.6–99.9%) | 1.000 |
| Yes | 2/338, 0.6% (0.1–2.1%) | 1/299, 0.3% (0.0–1.8%) | 3/637, 0.5% (0.1–1.4%) | ||
| Inflammatory status (CRP)6 | <5 mg/l | 290/318, 91.2% (87.5–94.1%) | 213/227, 93.8% (89.9–96.6%) | 503/545, 92.3% (89.7–94.4%) | 0.328 |
| ≥5 mg/l | 28/318, 8.8% (5.9–12.5%) | 14/227, 6.2% (3.4–10.1%) | 42/545, 7.7% (5.6–10.3%) | ||
1p-value from Fishers exact test for categorical variables.
22 missing values in Metro Manila region and 1 missing value in Negros Occidental region. Undernutrition is defined using BMI kg/m2: mild: <18.5–17; moderate: <17–16; severe: <16; none: ≥18.5.
313 missing values in Metro Manila region and 35 missing values in Negros Occidental region. Diabetes defined as HbA1c ≥ 6–5% or on current diabetes medication.
42 missing values in Metro Manila region and 3 missing values in Negros Occidental region. Moderate or Severe anaemia defined as haemoglobin<10 g/dL.
5only 41/299 patients were tested for HIV in Negros Occidental region, 35 missing values in Metro Manila.
6C-REactive Protein; Ref. 45.