Table II.
Chemotherapy toxic effects, worst grade per patient.
| Item | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
| Hematological | |||||
| White blood cells | 3 | 2 | 2 | 1 | 0 |
| Neutrophils | 2 | 1 | 3 | 2 | 0 |
| Platelets | 5 | 2 | 1 | 0 | 0 |
| Biochemical | |||||
| Creatinine | 0 | 0 | 0 | 0 | 0 |
| AST | 6 | 1 | 1 | 0 | 0 |
| ALT | 6 | 1 | 1 | 0 | 0 |
| Clinical | |||||
| Nausea | 2 | 2 | 2 | 0 | 0 |
| Vomiting | 1 | 0 | 0 | 0 | 0 |
| Diarrhoea | 1 | 0 | 0 | 0 | 0 |
| Mucositis | 0 | 0 | 0 | 0 | 0 |
| Alopecia | 1 | 3 | 1 | 0 | 0 |
| Fever | 2 | 0 | 0 | 0 | 0 |
| Infection | 0 | 0 | 0 | 1 | 0 |
| Neurological | 0 | 0 | 0 | 0 | 0 |
| Cardiac | 0 | 0 | 0 | 0 | 0 |
Toxic effects were assessed using the National Cancer Institute common toxicity criteria (version 1). Data are number of patients (%). Laboratory data available for 8 patients, clinical data for 6 patients. AST, aspartate aminotransferase; ALT, alanine aminotransferase.