Table 2. Immune cell landscape compared with gene expression.
Tumor purity | B cell | CD8+ T cell | CD4+ T cell | Macrophage | Neutrophil | Dendritic cell | |
---|---|---|---|---|---|---|---|
r | r | r | r | r | r | r | |
EMILIN1 | (−) | (+) | (−) | (++) | (++) | (++) | (++) |
EMILIN2 | (−) | (++) | (+) | (++) | (++) | (++) | (++) |
EMILIN3 | (−) | (+) | (+) | (+) | (+) | (++) | (+) |
MMRN1 | (‐‐) | (++) | (+) | (++) | (++) | (+++) | (+++) |
MMRN2 | (+) | (+) | (+) | (+) | (+) | (+) | (+) |
Note:
Categorized Pearson’s product-moment correlation of immune cell landscape of LGG compared with TCGA gene expression of EMILIN1, EMILIN2, EMILIN, MMRN1, MMRN2 (TIMER). r, categorized Pearson’s correlation coefficient; (‐‐), −0.5 to −0.3, weak negative association; (−), −0.3 to 0.1, little association; (+), +0.1 to 0.3, little association; (++) +0.3 to +0.5, weak positive association; (+++), +0.5 to +1.0, strong positive association.