Table 5.
Change in depression in study groups by participant characteristics.
| Variables | Run4Love intervention (N=150) | Usual care (N=150) | Mean between-group difference for change from baseline (95% CI)c | P valued | P value for interaction | ||||||||||
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|
N | Within-Group 3-month change in CES-D from baseline, mean (95% CI)a | N | Within-Group 3-month change in CES-D from baseline, mean (95% CI)b |
|
|
|
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| Age | .02 | ||||||||||||||
|
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<27 years | 68 | −7.29 (−9.31 to −5.27) | 65 | 1.28 (−0.59 to 3.15) | −8.57 (−11.30 to −5.83) | <.001 | ||||||||
|
|
≥27 years | 82 | −5.31 (−7.39 to −3.24) | 85 | −1.76 (−3.92 to 0.40) | −3.55 (−6.51 to −0.60) | .02 | ||||||||
| Gender | .89 | ||||||||||||||
|
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Male | 142 | −6.28 (−7.75 to −4.81) | 135 | −0.52 (−2.11 to 1.06) | −5.76 (−7.90 to −3.62) | <.001 | ||||||||
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|
Female | 8 | −4.88 (−15.33 to 5.58) | 15 | 0.31 (−4.09 to 4.70) | −5.18 (−13.65 to 3.28) | .22 | ||||||||
| BMI | .58 | ||||||||||||||
|
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<18.5 kg/m2 | 34 | −5.40 (−9.25 to −1.54) | 37 | 1.48 (−1.54 to 4.49) | −6.88 (−11.62 to −2.14) | .005 | ||||||||
|
|
≥18.5 kg/m2 | 116 | −6.45 (−7.98 to −4.91) | 113 | −1.07 (−2.78 to 0.64) | −5.38 (−7.64 to −3.11) | <.001 | ||||||||
| Education | .05 | ||||||||||||||
|
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≤high school | 52 | −4.27 (−6.44 to −2.10) | 66 | −1.12 (−3.56 to 1.32) | −3.15 (−6.46 to 0.16) | .06 | ||||||||
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>high school | 98 | −7.24 (−9.12 to −5.35) | 84 | 0.09 (−1.76 to 1.94) | −7.33 (−9.96 to −4.69) | <.001 | ||||||||
| Sexual orientation | .27 | ||||||||||||||
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Homosexual | 130 | −6.37 (−7.93 to −4.81) | 115 | −0.01 (−1.71 to 1.69) | −6.36 (−8.64 to −4.08) | <.001 | ||||||||
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Heterosexual | 20 | −5.14 (−9.46 to −0.82) | 35 | −1.86 (−4.95 to 1.24) | −3.29 (−8.31 to 1.73) | .19 | ||||||||
| Marital status | .006 | ||||||||||||||
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|
Married | 18 | −3.78 (−8.08 to 0.52) | 20 | −5.41 (−10.43 to −0.39) | 1.63 (−4.77 to 8.04) | .61 | ||||||||
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Unmarried | 132 | −6.54 (−8.09 to −4.99) | 130 | 0.32 (−1.19 to 1.83) | −6.86 (−9.01 to −4.71) | <.001 | ||||||||
| Family monthly income | .45 | ||||||||||||||
|
|
≥7000 yuan | 82 | −6.22 (−8.12 to −4.32) | 94 | 0.14 (−1.69 to 1.97) | −6.36 (−8.98 to −3.75) | <.001 | ||||||||
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|
>7000 yuan | 68 | −6.19 (−8.45 to −3.93) | 56 | −1.42 (−3.98 to 1.15) | −4.77 (−8.12 to −1.42) | .006 | ||||||||
| Employed | .17 | ||||||||||||||
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Employed | 123 | −5.68 (−7.29 to −4.08) | 128 | −0.63 (−2.25 to 0.99) | −5.05 (−7.32 to −2.79) | <.001 | ||||||||
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Unemployed | 27 | −8.59 (−12.09 to −5.09) | 22 | 0.66 (−3.22 to 4.54) | −9.25 (−14.33 to −4.18) | <.001 | ||||||||
| Duration of HIV infection | .99 | ||||||||||||||
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≤1 year | 54 | −6.62 (−9.15 to −4.10) | 56 | −0.86 (−3.48 to 1.76) | −5.77 (−9.36 to −2.17) | .002 | ||||||||
|
|
>1 year | 96 | −5.97 (−7.77 to −4.18) | 94 | −0.19 (−2.00 to 1.61) | −5.78 (−8.30 to −3.26) | <.001 | ||||||||
| Center for Epidemiologic Studies-Depression score | .83 | ||||||||||||||
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≤Baseline mean | 91 | −5.14 (−6.94 to −3.33) | 93 | 0.77 (−1.02 to 2.56) | −5.91 (−8.42 to −3.39) | <.001 | ||||||||
|
|
>Baseline mean | 59 | −7.86 (−10.30 to −5.43) | 57 | −2.42 (−4.96 to 0.12) | −5.44 (−8.91 to −1.97) | .002 | ||||||||
aOverall −6.21 (−7.66 to −4.76).
bOverall −0.44 (−1.92 to 1.03).
cOverall −5.77 (−7.82 to −3.71).
dOverall P value <.001.