Table 1.
DBS indications.
| Indication | Target(s) | Status |
|---|---|---|
| Parkinson’s | Subthalamic nucleus | Well-established |
| Internal globus pallidus | ||
| Essential tremor | Ventral intermediate thalamus | |
| Dystonia | Internal globus pallidus | |
| Parkinson’s | Pedunculopontine nucleus | Not widely implemented, still under investigation |
| Zona incerta | ||
| Essential tremor | Zona incerta | |
| Pain | Periaqueductal and periventricular grey matter | |
| Ventral posterolateral and posteromedial thalamus | ||
| Anterior cingulate cortex | ||
| OCD | Anterior limb of internal capsule | |
| Medial thalamus | ||
| Tourette’s | Internal globus pallidus | |
| Epilepsy | Hippocampus | |
| Depression | Subgenual cingulated | |
| Nucleus accumbens | ||
| Cluster headache | Posterior hypothalamus | |
| Addiction | Nucleus accumbens | Very limited investigation, largely hypothetical |
| Anorexia | Nucleus accumbens | |
| Obesity | Nucleus accumbens | |
| Alzheimer’s | Fornix | |
| Ventromedial prefrontal cortex | ||
| Huntington’s | Internal globus pallidus |
OCD: obsessive–compulsive disorder.