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The first experiment by Bliss and Lømo, performed in the autumn of 1968, on the effects of high-frequency stimulation on synaptic responses in the hippocampus of the anaesthetised rabbit. Because of drifting baselines, this figure was not included in Bliss and Lømo (1973), but the long-lasting potentiation of the responses in the tetanised pathway (filled circles) can be clearly seen. The moribund control pathway was coaxed back to life by repeated trains at the end of the experiment.
