Figure 6.

Spatial distributions of perfusion–diffusion mismatch tissue across six coronal slices (caudal to rostral) at 1 and 4 h after MCAO (a). The images displayed are from the median animal of each group. The red region depicts the perfusion deficit defined by applying an absolute threshold of 30 mL/100 g/min. The white region depicts the ADC lesion defined by applying an ADC threshold of 0.53 × 10⁻³ mm²/s. On slices where there was a perfusion deficit but no ADC lesion the perfusion deficit area was considered as mismatch tissue. Perfusion–diffusion mismatch volumes 1–4 h post-MCAO (b). There was no statistical difference between vehicle- and glucose-treated groups by repeated measures two-way ANOVA.