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. 2020 Mar 5;15(3):e0229922. doi: 10.1371/journal.pone.0229922

Table 2. Comparison of phenotypic values between Clusters 2 and 4.

Cluster 2 Cluster 4
FALSE TRUE p FALSE TRUE p
n 4172 324 2661 829
SEX (mean (SD)) 1.51 (0.50) 1.31 (0.46) <0.001 1.51 (0.50) 1.40 (0.49) <0.001
AGE (mean (SD)) 47.08 (11.00) 58.21 (8.46) <0.001 45.95 (10.31) 55.59 (9.16) <0.001
BAI (mean (SD)) 4.42 (0.34) 4.43 (0.33) 0.401 4.82 (0.41) 4.79 (0.39) 0.086
BMI (mean (SD)) 21.54 (2.54) 22.37 (2.50) <0.001 27.00 (3.16) 27.24 (3.15) 0.057
BODY_FAT_RATE (mean (SD)) 22.42 (6.14) 21.54 (5.81) 0.015 31.90 (6.65) 30.70 (6.59) <0.001
WHR (mean (SD)) 0.82 (0.06) 0.86 (0.06) <0.001 0.90 (0.06) 0.93 (0.05) <0.001
T_CHO (mean (SD)) 182.57 (30.34) 188.96 (34.44) <0.001 204.57 (33.68) 199.26 (33.84) <0.001
HDL_C (mean (SD)) 62.36 (12.41) 60.91 (12.87) 0.045 47.08 (9.60) 45.83 (9.30) 0.001
LDL_C (mean (SD)) 106.98 (26.35) 113.43 (30.59) <0.001 134.79 (30.01) 127.76 (30.36) <0.001
TG (mean (SD)) 64.31 (24.27) 68.61 (24.44) 0.002 148.48 (67.74) 162.38 (69.49) <0.001
FASTING_GLUCOSE (mean (SD)) 89.74 (6.93) 95.32 (12.04) <0.001 95.96 (9.28) 102.28 (13.25) <0.001
HBA1C (mean (SD)) 5.44 (0.32) 5.64 (0.40) <0.001 5.77 (0.39) 6.06 (0.54) <0.001
ALBUMIN (mean (SD)) 4.53 (0.32) 4.52 (0.20) 0.501 4.62 (0.35) 4.62 (0.21) 0.81
BUN (mean (SD)) 12.82 (3.29) 14.47 (3.41) <0.001 12.77 (3.13) 14.22 (3.34) <0.001
CREATININE (mean (SD)) 0.71 (0.18) 0.78 (0.18) <0.001 0.75 (0.20) 0.81 (0.20) <0.001
URIC_ACID (mean (SD)) 4.92 (1.19) 5.26 (1.15) <0.001 6.32 (1.44) 6.55 (1.45) <0.001
eGFR (mean (SD)) 106.53 (12.23) 96.28 (11.98) <0.001 104.30 (13.27) 94.50 (13.52) <0.001
microALB (mean (SD)) 8.70 (6.59) 10.27 (9.14) <0.001 12.22 (8.80) 14.41 (10.67) <0.001
T_BILIRUBIN (mean (SD)) 0.71 (0.24) 0.77 (0.24) <0.001 0.61 (0.23) 0.64 (0.23) <0.001
SGOT (mean (SD)) 22.13 (5.37) 23.86 (5.22) <0.001 24.98 (6.87) 26.41 (6.69) <0.001
SGPT (mean (SD)) 16.56 (7.01) 18.13 (6.86) <0.001 29.77 (14.87) 30.61 (13.62) 0.147
AFP (mean (SD)) 2.24 (1.75) 2.39 (1.63) 0.138 2.52 (1.73) 2.77 (1.70) <0.001
GAMMA_GT (mean (SD)) 14.52 (7.89) 15.86 (7.53) 0.003 30.40 (16.69) 31.15 (15.69) 0.256
WBC (mean (SD)) 5.25 (1.29) 5.22 (1.25) 0.723 6.72 (1.58) 6.68 (1.50) 0.458
RBC (mean (SD)) 4.62 (0.46) 4.65 (0.40) 0.391 5.00 (0.49) 4.96 (0.45) 0.081
HB (mean (SD)) 13.62 (1.52) 13.93 (1.16) <0.001 14.50 (1.60) 14.64 (1.34) 0.02
HCT (mean (SD)) 41.85 (5.71) 42.29 (3.29) 0.178 44.86 (7.07) 44.92 (3.95) 0.82
PLATELET (mean (SD)) 222.67 (48.23) 209.61 (48.58) <0.001 257.14 (56.99) 241.27 (53.29) <0.001
SYSTOLIC (mean (SD)) 110.19 (14.52) 125.41 (17.81) <0.001 121.74 (15.63) 132.59 (16.47) <0.001
DIASTOLIC (mean (SD)) 68.43 (9.48) 75.00 (10.13) <0.001 76.79 (10.55) 80.44 (10.28) <0.001
MAP (mean (SD)) 127.97 (16.55) 141.80 (18.21) <0.001 142.96 (18.25) 151.45 (17.51) <0.001
PP (mean (SD)) 41.77 (9.81) 50.42 (12.79) <0.001 44.95 (10.58) 52.15 (13.33) <0.001

Abbreviations are the same as those used in Fig 1. TRUE represents subjects afflicted with diabetes, dyslipidemia or hypertension.