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. 2020 Feb 17;23(3):100921. doi: 10.1016/j.isci.2020.100921

Table 1.

Expression of Glutamate Receptors and Transporters in β-Tanycytes

Expression in Beta Tanycytes (CTgeomean housekeeping genes - Ctgene ± SEM) Short Name of the Gene Description
Genes Expressed in Tanycytes

5.52 ± 0.92 SLC1A1 Solute carrier family 1, member 1
4.50 ± 0.34 SLC1A2 Solute carrier family 1, member 2
−0.15 ± 0.26 SLC1A3 Solute carrier family 1, member 3
2.89 ± 0.17 GRIA1 Glutamate receptor, ionotropic, AMPA1 (alpha 1)
4.37 ± 0.51 GRIA2 Glutamate receptor, ionotropic, AMPA2 (alpha 2)
5.97 ± 0.68 GRIK2 Glutamate receptor, ionotropic, kainate 2 (beta 2)
−0.59 ± 0.10 GRIK3 Glutamate receptor, ionotropic, kainate 3
5.81 ± 0.27 GRIK4 Glutamate receptor, ionotropic, kainate 4
2.57 ± 0.35 GRIK5 Glutamate receptor, ionotropic, kainate 5 (gamma 2)
3.15 ± 0.09 GRIN3A Glutamate receptor ionotropic, NMDA3A
5.29 ± 0.16 GRM4 Glutamate receptor, metabotropic 4
1.57 ± 0.25 DIO2 Deiodinase, iodothyronine, type II
5.46 ± 0.31 DAGLA Diacylglycerol lipase, alpha

Genes Not Expressed in Tanycytes

8.07 ± 0.61 SLC1A6 Solute carrier family 1, member 6
UD SLC1A7 Solute carrier family 1, member 7
6.83 ± 1.68 GRIA3 Glutamate receptor, ionotropic, AMPA3 (alpha 3)
6.85 ± 0.58 GRIA4 Glutamate receptor, ionotropic, AMPA4 (alpha 4)
10.24 ± 0.33 GRIK1 Glutamate receptor, ionotropic, kainate 1
6.80 ± 0.75 GRIN1 Glutamate receptor, ionotropic, NMDA1 (zeta 1)
6.88 ± 0.30 GRIN2A Glutamate receptor, ionotropic, NMDA2A (epsilon 1)
6.54 ± 0.21 GRIN2B Glutamate receptor, ionotropic, NMDA2B (epsilon 2)
UD GRIN2C Glutamate receptor, ionotropic, NMDA2C (epsilon 3)
8.26 ± 0.62 GRIN2D Glutamate receptor, ionotropic, NMDA2D (epsilon 4)
UD GRIN3B Glutamate receptor, ionotropic, NMDA3B
11.77 ± 1.98 GRM1 Glutamate receptor, metabotropic 1
UD GRM2 Glutamate receptor, metabotropic 2
6.88 ± 1.21 GRM3 Glutamate receptor, metabotropic 3
6.38 ± 0.73 GRM5 Glutamate receptor, metabotropic 5
UD GRM6 Glutamate receptor, metabotropic 6
9.20 ± 0.27 GRM7 Glutamate receptor, metabotropic 7
UD GRM8 Glutamate receptor, metabotropic 8
8.08 ± 0.41 TRHR1 Thyrotropin-releasing hormone receptor 1
6.86 ± 1.59 TRHR2 Thyrotropin-releasing hormone receptor 2

Genes were considered to be expressed in β-tanycytes if the ΔCT value was lower than the ΔCT of GRM5. See also Figure S4 and Table S1.