Figure 2.

Survival analysis of human PDAC classified using IPA-EMT gene set. Hierarchical clustering was performed on 118 PDAC patients data retrieved from NCBI (GSE62165) using 55 EMT-associated genes [12]. H -settings: RNA expression = 2log values; dissimilarity = Pearson’s distance, HC = complete linkage, normalized rows = Z-score, seriation = multifragment heuristics. This signature could separate the patients into two groups (EMT-high patients and EMT-low patients). Using corresponding survival data and log-rank test, disease-free survival (DFS) and overall survival (OS) of these 118 patients were analyzed [25].