Supplementary Fig. 1.
Pilot studies testing urinary albumin and renal Smad3 activation in STZ-injected mice.
A. Western blot analysis showing protein expression of p-Smad3 and Smad3; B. urinary albumin/creatinine ratio. Data represent the mean ± S.E.M. for 6–8 mice. *P < 0.05, **P < 0.01 compared to ND. ND: non-diabetic mice; DM: STZ-induced diabetic mice; I/R and DM + I/R: non-diabetic mice and STZ-induced diabetic mice were subject to ischemia reperfusion injury.