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. 2020 Jan 17;105(4):1098–1111. doi: 10.1210/clinem/dgaa023

Figure 2.

Figure 2.

Total amygdala, hippocampus, and prefrontal cortex (PFC) volumes in youth with classical CAH and controls by hemisphere. Plots reflect means and standard error of volumes for: A) amygdala, B) hippocampus, and C) prefrontal cortex (PFC) regions of interest. A) Trend level difference was seen for smaller total right amygdala volumes in CAH compared to control youth (†P = 0.10). B) Left hippocampus is significantly smaller in CAH compared to control youth (** P ≤ 0.01). C) Bilateral superior frontal (SF) cortex volumes (* P ≤ 0.05) and caudal middle frontal (MF) cortex volumes (* P ≤ 0.05) were significantly smaller in CAH compared to control youth. Left rostral middle frontal volumes were significantly smaller in CAH compared to control youth (** P ≤ 0.01). Trend level difference was seen for smaller right lateral orbitofrontal cortex (OFC) volumes in CAH compared to control youth (†P = 0.07). D) Significant PFC regions of interest mapped to the cortex for visualization (dark gray).