Table 4.
Hippocampal subfields mean and SD for CAH and control youth
| CAH (n = 27) | Control (n = 35) | Group-by-Region Post-hoc Test | ||||
|---|---|---|---|---|---|---|
| Total | RVF | Total | RVF | Total† | RVF‡ | |
| Parasubiculum | ||||||
| Right | 69.15 ± 16.08 | 0.021 ± 0.004 | 70.27 ± 14.83 | 0.020 ± 0.004 | Meansadj = 7.76, χ 2(1) = 0.47; P = 0.49 | Meansadj= -0.0008, χ 2(1) = 0.49; P = 0.48 |
| Left | 68.49 ± 12.81 | 0.022 ± 0.004 | 70.23 ± 12.14 | 0.021 ± 0.004 | ||
| Presubiculum | ||||||
| Right | 291.48 ± 67.89 | 0.085 ± 0.007 | 319.14 ± 36.62 | 0.089 ± 0.006 | Meansadj = -20.67, χ 2(1) = 3.36; P = 0.07 | Meansadj = -0.003, χ 2(1) = 7.99; P = 0.005 |
| Left | 285.38 ± 47.4 | 0.089 ± 0.009 | 317.45 ± 36.61 | 0.092 ± 0.005 | ||
| Subiculum | ||||||
| Right | 401.79 ± 111.56 | 0.117 ± 0.01 | 429.61 ± 55.35 | 0.120 ± 0.007 | Meansadj = -25.76, χ 2(1) = 5.22; P = 0.02 | Meansadj = -0.003, χ 2(1) = 6.29; P = 0.01 |
| Left | 381.15 ± 51.69 | 0.119 ± 0.007 | 423.23 ± 54.67 | 0.122 ± 0.007 | ||
| CA1 | ||||||
| Right | 626.94 ± 107.6 | 0.184 ± 0.009 | 666.49 ± 87.09 | 0.185 ± 0.011 | Meansadj = -42.40, χ 2(1) = 14.13; P < 0.0002 | Meansadj= -0.0025, χ 2(1) = 4.89; P = 0.03 |
| Left | 571.1 ± 61.85 | 0.179 ± 0.008 | 634.74 ± 82.84 | 0.183 ± 0.009 | ||
| CA3 | ||||||
| Right | 227.15 ± 39.9 | 0.067 ± 0.007 | 229.55 ± 32.18 | 0.064 ± 0.006 | Meansadj = 4.05, χ 2(1) = 0.13; P = 0.71 | Meansadj = 0.003, χ 2(1) = 6.25; P = 0.01 |
| Left | 209.96 ± 24.22 | 0.066 ± 0.006 | 217.84 ± 29.65 | 0.063 ± 0.006 | ||
| Dentate gyrus (DG) | ||||||
| Right | 289.33 ± 48.44 | 0.085 ± 0.005 | 304.37 ± 38.47 | 0.085 ± 0.005 | Meansadj = -8.09, χ 2(1) = 0.51; P = 0.47 | Meansadj = 0.0008, χ 2(1) = 0.46; P = 0.50 |
| Left | 272.55 ± 27.73 | 0.086 ± 0.004 | 292.08 ± 35.31 | 0.084 ± 0.004 | ||
Total reflects larger or smaller subregion volume; RVF (relative volume fraction) reflects the fraction of the total hippocampus that is included in this subregion.
Meansadj† (adjusted means for BMI z-score, bone age standard deviations, and ICV).
Meansadj‡ (adjusted means for BMI z-score and bone age standard deviation).