Table 2. Distribution of thyroid cancer cases and controls and corresponding odds ratios (OR) according to selected past history and family history.
Variable | Cases | Controls | OR (95% CI)* |
Disease of the thyroid gland | |||
Goiter | 25 | 1 | 25.00 (3.39-184.5) |
Nodule | 5 | 1 | 5.00 (0.58-42.8) |
Hyperthyroidism | 4 | 5 | 0.80 (0.22-2.98) |
Hypothyroidism | 2 | 1 | 2.00 (0.18-22.1) |
Other diseases | 4 | 2 | 2.00 (0.37-10.9) |
Radiotherapy to the head and neck region | 5 | 0 | infinity |
Allergic conditions | |||
Bronchial asthma | 5 | 4 | 1.25 (0.34-4.66) |
Urticaria | 39 | 40 | 0.97 (0.60-1.57) |
Other allergic diseases | 28 | 22 | 1.32 (0.73-2.39) |
Antihistamines regular use longer than one year | 1 | 2 | 0.50 (0.05-5.51) |
Other medical histories | |||
Tonsillectomy | 5 | 4 | 1.25 (0.34-4.66) |
Diuretics regular use longer than one year | 3 | 5 | 0.60 (0.14-2.51) |
Anti-hypertensive agents regular use longer than one year | 7 | 16 | 0.40 (0.16-1.03) |
Family history of cancer | |||
Thyroid cancer, any first-degree relative | 5 | 0 | infinity |
Any site, any first-degree relative | 93 | 68 | 1.48 (1.04-2.11) |
Any site, parent | 70 | 58 | 1.24 (0.85-1.79) |
Any site, father | 48 | 39 | 1.27 (0.81-1.98) |
Any site, mother | 26 | 23 | 1.14 (0.64-2.02) |
Any site, sibling | 28 | 11 | 2.70 (1.31-5.58) |
Any site, brother | 11 | 6 | 1.83 (0.68-4.96) |
Any site, sister | 18 | 5 | 4.25 (1.43-12.63) |
Any site, son | 0 | 0 | - |
Any site, daughter | 1 | 1 | 1.00 (0.06-15.99) |
* : Matched on city, age, sex, and radiation exposure
CI: confidence interval