TABLE 1.
Categories | Composition | Function | Classes or examples |
Fatty acids | Carboxylic acid + hydrocarbon chain; synthesized by chain elongation of an acetyl-CoA with malonyl-CoA | Building blocks to complex lipids | SFA, MUFA, PUFA |
Glycerolipids | FA + glycerol; may have sugar residues | Energy storage, cell signaling | TAG, DAG, MAG |
Glycerophospholipids | Polar head group + glycerol group, may contain LCFA | Membrane composition, cell signaling | PC, PE, PS, PI, PA |
Sphingolipids | Sphingoid base + LCFA-CoA | Membrane and lipoprotein composition, cell signaling | Ceramides, Phosphosphingolipids, glycosphingolipids |
Sterols | Hydroxyl group + steroid | Membrane, precursor to hormones and vitamins | Cholesterol, bile acids |
Prenols | Isopentenyl diphosphate + dimethylallyl diphosphate | Antioxidants, vitamin precursor | Quinone, ubiquinone, Vitamin E, Vitamin K |
Saccharolipids | FAs + sugar backbone | Membrane components | Glucosamine |
Polyketides | Acetyl + propionyl polymerization | Secondary metabolites | Tetracycline, erythromycin |
List of the different categories of lipids, as defined by the LIPID MAPS consortium, with summaries of their average composition, functions and classes. FA, fatty acid; SFA, short chain fatty acid; MUFA, mono-unsaturated fatty acid; PUFA, poly-unsaturated fatty acid; TAG, triacylglycerol; DAG, diacylglycerol; MAG, monoacylglycerol; PC, phospatidylcholine; PE, phosphatidylethanolamine; PS, phosphatidylserine; PI, phosphatiylinositol; PA, phosphatidic acid; LCFA-CoA, long-chain fatty acid-coenzyme A.