Table 2.
Treatment group | Low (n = 35) | Medium (n = 37) | High (n = 29) | ||||||
---|---|---|---|---|---|---|---|---|---|
Cognitive test | Baseline | Week 12 | Change from baseline | Baseline | Week 12 | Change from baseline | Baseline | Week 12 | Change from baseline |
RTI | 373.66 ± 51.83a | 367.06 ± 59.34 | − 6.60 ± 55.11 | 345 ± 45.66 | 354.15 ± 67 | 9.15 ± 55.07 | 349.33 ± 61.70 | 363.99 ± 70.79 | 14.66 ± 52.64 |
SSP | 5.51 ± 1.06 | 5.77 ± 1.14 | 0.25 ± 1.22 | 5.65 ± 1.18 | 5.68 ± 1.23 | 0.03 ± 1.55 | 5.62 ± 1.18 | 5.76 ± 0.83 | 0.14 ± 1.36 |
SWM | 33.86 ± 19.09 | 29.11 ± 16.95 | − 4.74 ± 15.74 | 28.7 ± 17.59 | 28.92 ± 17.85 | 0.22 ± 17.42 | 30.45 ± 16.04 | 27.90 ± 16.08 | − 2.55 ± 15.07 |
PRM | 2054.25 ± 395.87 | 2083.14 ± 544.32 | 28.89 ± 417.47 | 2138.94 ± 587.38 | 1903.244 ± 434.09 | − 235.7 ± 557.83 | 1920.65 ± 458.59 | 1969.56 ± 568.19 | 48.91 ± 565.60 |
MTS | 2836.70 ± 732.05 | 2518.54 ± 735.28 | − 318.16 ± 585.35 | 2846.98 ± 796.82 | 2456.46 ± 606.2 | − 390.52 ± 814.11 | 2694.54 ± 597.66 | 2535.90 ± 607.23 | − 158.64 ± 572.23 |
No significant differences were observed between the groups for any of the outcomes measured using an ANCOVA to compare post-intervention (week 12) cognitive function with baseline measures as covariates
RTI five-choice reaction time measured as reaction time latency (ms), SSP spatial span measured as longest sequence length recalled correctly, SWM spatial working memory measured as total errors made, PRM pattern recognition memory measured as mean correct latency (ms), MTS match to sample visual search measured as mean correct reaction time (ms)
aMean ± SD (all such values)