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. 2019 Feb 26;59(2):609–619. doi: 10.1007/s00394-019-01929-2

Table 3.

Associations between (a) the type of nursing and (b) milk nutrients with performance in relational binding

Relational binding (memory) (a) Nursing (b) Nutrients
N Unadjusted mean ± SD Adjusted mean differences (95% CI)b, d N Unadjusted mean ± SD Adjusted mean differences (95% CI)c, d
Breast + bottle or bottle only At breast only At breast only Formula only Breast milk + formula or breast milk only Breast milk + formula or breast milk only
6 months
 Lag 0 trials (Time binsa)
  1000-ms Bin 1 34 0.31 ± 0.17 0.41 ± 0.21 0.13 (− 0.07, 0.33) 90 0.36 ± 0.22 0.23 ± 0.14 − 0.10 (− 0.23, 0.04)
  1000-ms Bin 2 31 0.28 ± 0.19 0.32 ± 0.21 − 0.04 (− 0.20, 0.11) 85 0.32 ± 0.26 0.28 ± 0.21 − 0.02 (− 0.18, 0.13)
  1000-ms Bin 3 29 0.30 ± 0.36 0.27 ± 0.28 − 0.08 (− 0.46, 0.31) 78 0.30 ± 0.32 0.24 ± 0.23 − 0.14 (− 0.35, 0.06)
 Lag 2 trials (Time binsa)
  1000-ms Bin 1 33 0.43 ± 0.29 0.42 ± 0.31 − 0.07 (− 0.36, 0.21) 85 0.36 ± 0.23 0.43 ± 0.17 0.07 (− 0.07, 0.22)
  1000-ms Bin 2 28 0.42 ± 0.17 0.40 ± 0.32 0.08 (− 0.19, 0.35) 81 0.35 ± 0.24 0.36 ± 0.29 0.06 (− 0.11, 0.24)
  1000-ms Bin 3 24 0.29 ± 0.26 0.43 ± 0.30 0.41 (0.07, 0.74)e 70 0.46 ± 0.34 0.40 ± 0.33 0.04 (− 0.21, 0.29)
41 months
 Accuracy in food block 57 3.13 ± 1.07 2.84 ± 0.85 − 0.27 (− 0.86, 0.32) 109 2.89 ± 1.18 3.00 ± 1.06 0.25 (− 0.41, 0.91)
 Accuracy in face block 57 2.35 ± 0.88 2.92 ± 1.09 0.67 (0.04, 1.29)e 108 2.56 ± 1.09 2.63 ± 0.77 0.30 (− 0.29, 0.89)
 Combined food and face accuracy 58 5.41 ± 1.52 5.65 ± 1.44 0.45 (− 0.49, 1.39) 109 5.42 ± 1.67 5.63 ± 1.41 0.59 (− 0.33, 1.51)
 Inference memory accuracy 56 1.23 ± 0.76 1.40 ± 0.91 0.29 (− 0.25, 0.84) 106 1.61 ± 0.87 1.25 ± 0.68 − 0.15 (− 0.64, 0.34)
54 months
 Lag 0 trials
  Accuracy 52 0.55 ± 0.29 0.67 ± 0.31 − 0.03 (− 0.26, 0.20) 115 0.55 ± 0.31 0.59 ± 0.26 0.02 (− 0.14, 0.19)
  % Looking to correct match 52 0.37 ± 0.17 0.40 ± 0.16 − 0.09 (− 0.23, 0.04) 114 0.43 ± 0.21 0.45 ± 0.17 0.01 (− 0.11, 0.11)
 Lag 2 trials
  Accuracy 52 0.41 ± 0.22 0.49 ± 0.32 0.08 (− 0.15, 0.32) 115 0.41 ± 0.27 0.53 ± 0.26 0.13 (− 0.02, 0.28)
  % Looking to correct match 52 0.36 ± 0.15 0.39 ± 0.09 0.12 (0.01, 0.22)e 113 0.34 ± 0.13 0.42 ± 0.12 0.06 (− 0.01, 0.13)

aTime bins are defined in 1000-ms blocks after the pictures appear on the screen

bValues are adjusted mean differences (95% CI) from the reference group (Breast + bottle or bottle only)

cValues are adjusted mean differences (95% CI) from the reference group (Formula only)

dValues are adjusted for ethnicity (Chinese, Malay and Indian), maternal education (non-tertiary and tertiary), birth weight category (SGA, AGA, and LGA), 26-week STAI-state scores (continuous), child’s sex, and age during assessment (continuous)

eValues are P < 0.05 compared to the reference group